Epithelial-Myoepithelial Carcinoma of Salivary Glands: A Tertiary Center Experience
Introduction Epithelial-myoepithelial carcinoma (EMC) is a rare, biphasic malignant tumor affecting the salivary glands. It represents less than 1% of all salivary gland tumors. This study aims to present a single-center experience regarding the diagnosis, management, and prognosis of EMC. Methods This study was…
2026 1,884 reads 0 citations
Original Articles
Epithelial-Myoepithelial Carcinoma of Salivary Glands: A Tertiary Center Experience
IntroductionEpithelial-myoepithelial carcinoma (EMC) is a rare, biphasic malignant tumor affecting the salivary glands. It represents less than 1% of all salivary gland tumors. This study aims to present a single-center experience regarding the diagnosis, management, and prognosis of EMC.
MethodsThis study was conducted between February 2020 and December 2025. Patients with a histopathologically confirmed diagnosis of epithelial-myoepithelial carcinoma were identified. Complete medical records containing demographics, clinical presentation, imaging results, histological features, treatment approaches, and follow-up results were included in the cases.
ResultsFive patients were identified, of which 4 (80%) were females. The mean age was 56 ± 9.38 years. Two patients (40%) presented with painless post-auricular swelling, 1 (20%) with submandibular swelling, and 2 (40%) were incidental findings. Histopathological examination confirmed EMC in all cases. Free margins were achieved in 3 tumors (60%). No recurrence was observed during a mean follow-up of 24 ± 28.92 months.
ConclusionEpithelial-myoepithelial carcinoma is a very rare tumor. It requires histopathological evaluation for accurate diagnosis, and complete surgical excision offers favorable short-term outcomes. Further studies are needed to better define its clinical characteristics and outcomes.
Keywords Epithelial-myoepithelial carcinoma Salivary gland neoplasm Parotidectomy Biphasic tumor All subjects
Barw Medical Journal. 2026;4(1):13–18