Tracing Hematological Shifts in Pregnancy: How Anemia and Thrombocytopenia Evolve Across Trimesters
Introduction Given pregnancy's significant impact on hematological parameters, monitoring these changes across trimesters is crucial. This study aims to evaluate hematological profiles in pregnant women, primarily focusing on the prevalence of anemia and thrombocytopenia throughout the different trimesters. Methods…
2025 1,645 reads 0 citations
Original Articles
Tracing Hematological Shifts in Pregnancy: How Anemia and Thrombocytopenia Evolve Across Trimesters
IntroductionGiven pregnancy's significant impact on hematological parameters, monitoring these changes across trimesters is crucial. This study aims to evaluate hematological profiles in pregnant women, primarily focusing on the prevalence of anemia and thrombocytopenia throughout the different trimesters.
MethodsThis retrospective cross-sectional study was conducted at Smart Health Tower from March to December 2024, with ethical approval from Kscien Organization. Pregnant women aged 18-45 years in any trimester were included, excluding those with pre-existing hematological disorders or significant complications. Blood samples were collected during routine antenatal visits for hematological analysis. Data were analyzed using IBM SPSS version 26.0, with statistical significance set at p<0.05.
ResultsThis study included 243 pregnant women, with a mean age of 29.91 ± 6.32 years. The average hematological parameters were as follows: white blood cell count 9.45 ± 2.10 × 10⁹/L, red blood cell count 4.21 ± 0.45 × 10¹²/L, hemoglobin 11.93 ± 1.03 g/dL, and platelet count 239.11 ± 59.47 × 10⁹/L. Anemia and thrombocytopenia were identified in 16.0% and 5.0% of participants, respectively, with significant trimester-related variations (p= 0.033, p= 0.006). The highest prevalence of anemia (30.8%) was observed in women aged 26–30 years.
ConclusionSignificant changes in hematological parameters across pregnancy trimesters highlight the need for regular monitoring to diagnose and manage anemia, thrombocytopenia, and other abnormalities, ensuring optimal maternal and fetal health.
Keywords Maternal health Thrombocytopenia Anemia Antenatal care All subjects
Barw Medical Journal. 2025;3(2)