Kikuchi-Fujimoto Disease Coexistent with Papillary Thyroid Carcinoma: A Report of Two Cases
Introduction Kikuchi-Fujimoto Disease (KFD), characterized by histiocytic necrotizing lymphadenitis, is a rare condition of unknown etiology. Diagnosis is dependent on lymph node biopsy. Despite its self-limiting nature, accurate identification is essential to exclude more serious conditions. This paper reports on two…
2025 1,092 reads 0 citations
Case Reports
Kikuchi-Fujimoto Disease Coexistent with Papillary Thyroid Carcinoma: A Report of Two Cases
IntroductionKikuchi-Fujimoto Disease (KFD), characterized by histiocytic necrotizing lymphadenitis, is a rare condition of unknown etiology. Diagnosis is dependent on lymph node biopsy. Despite its self-limiting nature, accurate identification is essential to exclude more serious conditions. This paper reports on two cases of KFD coexisting with papillary thyroid carcinoma (PTC).
Case presentationTwo cases of KFD related to papillary thyroid carcinoma (PTC) are described. In Case 1, a 25-year-old woman experienced submental swelling, fever, and exhaustion. Subsequent tests revealed a thyroid lesion and cervical lymphadenopathy, which were confirmed as PTC and KFD. In Case 2, a 39-year-old female patient had right neck swelling, prompting a complete thyroidectomy that revealed papillary thyroid cancer with KFD in cervical lymph nodes.
ConclusionThe conclusion emphasizes the importance of considering KFD while highlighting its masquerading nature and the unique scenario of its coexistence with PTC.
Keywords Kikuchi-Fujimoto Disease Papillary thyroid carcinoma Co-occurrence Thyroid cancer All subjects
Barw Medical Journal. 2025;3(2)