Abdulwahid M. Salih, Rebaz M. Ali, Ari M. Abdullah, Aras J. Qaradakhy, Ahmed H. Ahmed, Imad J. Habibullah, Sarwat T. San Ahmed, Mariwan L. Fatah and 4 more
Introduction Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignant salivary gland tumor that can lead to severe complications and carries a risk of distant metastasis. This study aims to provide a comprehensive overview of CXPA through a case series and a review of the literature. Methods This was a…
Carcinoma ex Pleomorphic Adenoma: A Case Series and Literature Review
Abdulwahid M. Salih, Rebaz M. Ali, Ari M. Abdullah, Aras J. Qaradakhy, Ahmed H. Ahmed, Imad J. Habibullah, Sarwat T. San Ahmed, Mariwan L. Fatah and 4 more
IntroductionCarcinoma ex pleomorphic adenoma (CXPA) is a rare malignant salivary gland tumor that can lead to severe complications and carries a risk of distant metastasis. This study aims to provide a comprehensive overview of CXPA through a case series and a review of the literature.
MethodsThis was a single-center retrospective case series. The patients were included from November 2018 to December 2024. All confirmed cases of CXPA that were diagnosed and managed with complete clinical data were included in this study. Cases with incomplete data were excluded.
ResultsSix patients were included, with ages ranging from 45 to 88 years (mean ± SD: 64 ± 15.36; median: 62). Most were male (66.7%), with an even distribution of occupations. All presented with preauricular swelling lasting 2 to 10 years, and three had left-sided tumors. Fine needle aspiration identified 33.3% as benign and 16.7% as malignant. Ultrasound examination showed solid tumors in four cases, three of which were well-defined. Three (50%) underwent total parotidectomy, and three (50%) underwent superficial parotidectomy. Histopathological examination revealed adenocarcinoma ex pleomorphic adenoma in 50% and squamous cell carcinoma ex pleomorphic adenoma in 16.7%. Tumor sizes ranged from 3.5 to 6 cm (mean: 4.73 ± 1.24 cm). Capsular invasion was present in all cases, with lymph node involvement in 33.3%, lympho-vascular invasion in 16.7%, and perineural invasion in 50%. Adjuvant therapy included radiotherapy or chemoradiotherapy.
ConclusionAlthough CXPA is very rare, it is a serious condition; surgical approach with or without adjuvant therapy may result in preferable outcomes.
Abdulwahid M. Salih, Shko H. Hassan, Rezheen J. Rashid, Zanyar A. Mohammed, Ahmed L. Ali, Ahmad H. Awakhti, Marwan N. Hassan, Berun A. Abdalla and 1 more
Introduction Pneumoparotid is a rare condition characterized by the presence of air in the parotid gland, usually caused by the retrograde flow of air through the parotid duct. This report presents a rare occurrence of self-induced pneumoparotid. Case presentation A-41-year-old female presented with a recurrent…
Self-Induced Pneumoparotid as a Result of Covering Mouth While Coughing: A Case Report
Abdulwahid M. Salih, Shko H. Hassan, Rezheen J. Rashid, Zanyar A. Mohammed, Ahmed L. Ali, Ahmad H. Awakhti, Marwan N. Hassan, Berun A. Abdalla and 1 more
IntroductionPneumoparotid is a rare condition characterized by the presence of air in the parotid gland, usually caused by the retrograde flow of air through the parotid duct. This report presents a rare occurrence of self-induced pneumoparotid.
Case presentationA-41-year-old female presented with a recurrent painless right-sided parotid gland swelling for one month. She reported covering her mouth with her hands while coughing. Clinical examination revealed a right parotid swelling inferior to her right ear. The mass was non-tender and compressible. The neck and skull base computed tomography with contrast revealed a large thin wall cystic space with small air bubbles in the course of Stenson's duct. The patient underwent conservative management with good outcome.
ConclusionPneumoparotid is an extremely uncommon condition characterized by the presence of air in the parotid gland. Diagnostic imaging techniques such as ultrasound, sialography, or CT scans are valuable in confirming the diagnosis.
