Hydatid Disease of The Brain Parenchyma: A Systematic Review Fattah H. Fattah, Azad Star Hattam, Zana Omar kak Abdullah, Khanda A. Anwar, Rezhen J. Rashid, Abdullah K. Ghafour, Alaa B. Latif, Hiwa O. Abdullah and 2 more Introduction Isolated brain hydatid disease (BHD) is an extremely rare form of echinococcosis. A prompt and timely diagnosis is a crucial step in disease management. This study is a systematic review of studies on intra-parenchymal BHD. Methods Studies that had the following properties were included: 1) The… 2025 1,150 reads 2 citations doi:10.58742/bmj.vi.203 Full text PDF XML Read abstract — read the abstract for Hydatid Disease of The Brain Parenchyma: A Systematic Review Review Articles Hydatid Disease of The Brain Parenchyma: A Systematic Review Fattah H. Fattah, Azad Star Hattam, Zana Omar kak Abdullah, Khanda A. Anwar, Rezhen J. Rashid, Abdullah K. Ghafour, Alaa B. Latif, Hiwa O. Abdullah and 2 more IntroductionIsolated brain hydatid disease (BHD) is an extremely rare form of echinococcosis. A prompt and timely diagnosis is a crucial step in disease management. This study is a systematic review of studies on intra-parenchymal BHD. MethodsStudies that had the following properties were included: 1) The intra-parenchymal brain infection had been confirmed by diagnostic modalities, surgical findings, or histopathology. 2) The patient details were provided in the study. 3) The cystic lesion [s] were located intracranially. ResultsAltogether, 112 studies with a sample size of 178 cases met the inclusion criteria. Males (60.1%) showed a higher prevalence of the disease than females (38.2%). Most of the cases (64%) were affected during the first and second decades of their lives. Left-side multi-lobe involvement was the most common type of involvement (28.1%), followed by right-side multi-lobe involvement (26.4%). Surgery was the primary treatment option (97.2%), with the Dowling technique or the modified Arana-Iniguez method as the preferred approach. The total recurrence and mortality rates were 7.3% and 3.4%, respectively. ConclusionThe definitive treatment for BHD is surgery, with the aim of removing cysts intact or excising mass lesions completely. A history of cyst rupture during operation may increase the likelihood of recurrence, and an extensive follow-up is required. Keywords Brain · Hydatidosis · Cystic · Alveolar · Hydatid cyst · Intra-axial lesions All subjects Barw Medical Journal. 2025;3(4):26–44 Read the article PDF XML